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Gene Family: Basic leucine zipper proteins

Also known as : "bZIP domain containing"

BZIP domain: The Basic Leucine Zipper Domain ( bZIP domain ) is found in many DNA binding eukaryotic proteins. One part of the domain contains a region that mediates sequence specific DNA binding properties and the leucine zipper that is required to hold together (dimerize) two DNA binding regions. The DNA binding region comprises a number of basic amino acids such as arginine and lysine. Proteins containing this domain are transcription factors. [Source: Wikipedia]

Family contains the following subsets

Genes contained within the family: 49

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
ATF1 activating transcription factor 1 TREB36 12q13.12
ATF2 activating transcription factor 2 CREB2 TREB7, CRE-BP1, HB16 2q31.1
ATF3 activating transcription factor 3 1q32.3
ATF4 activating transcription factor 4 TXREB TAXREB67, CREB-2 22q13.1
ATF5 activating transcription factor 5 19q13.33
ATF6 activating transcription factor 6 ATF6A 1q23.3
ATF6B activating transcription factor 6 beta CREBL1 G13 6p21.3
ATF7 activating transcription factor 7 ATFA 12q13.13
BACH1 BTB domain and CNC homolog 1 BACH-1, BTBD24 21q21.3
BACH2 BTB domain and CNC homolog 2 BTBD25 6q15
BATF basic leucine zipper ATF-like transcription factor B-ATF, SFA-2, BATF1 14q24.3
BATF2 basic leucine zipper ATF-like transcription factor 2 MGC20410 11q13.1
BATF3 basic leucine zipper ATF-like transcription factor 3 JUNDM1, SNFT, JDP1 1q32.3
CEBPA CCAAT/enhancer binding protein alpha CEBP C/EBP-alpha 19q13.11
CEBPB CCAAT/enhancer binding protein beta TCF5 LAP, CRP2, NFIL6, IL6DBP, C/EBP-beta 20q13.13
CEBPD CCAAT/enhancer binding protein delta CRP3, CELF, C/EBP-delta, NF-IL6-beta 8q11.21
CEBPE CCAAT/enhancer binding protein epsilon CRP1 14q11.2
CEBPG CCAAT/enhancer binding protein gamma GPE1BP, IG/EBP-1 19q13.11
CREBL2 cAMP responsive element binding protein like 2 12p13.1
CREBZF CREB/ATF bZIP transcription factor ZF 11q14.1
CREB1 cAMP responsive element binding protein 1 2q33.3
CREB3 cAMP responsive element binding protein 3 LZIP, Luman, sLZIP 9p13.3
CREB3L1 cAMP responsive element binding protein 3 like 1 OASIS 11p11.2
CREB3L2 cAMP responsive element binding protein 3 like 2 BBF2H7, TCAG_1951439 7q33
CREB3L3 cAMP responsive element binding protein 3 like 3 CREB-H 19p13.3
CREB3L4 cAMP responsive element binding protein 3 like 4 AIbZIP, CREB4, CREB3, hJAL, ATCE1 1q21.3
CREB5 cAMP responsive element binding protein 5 H_GS165L15.1, CRE-BPA 7p15.1-p14.3
CREM cAMP responsive element modulator hCREM-2 10p11.21
FOS Fos proto-oncogene, AP-1 transcription factor subunit c-fos, AP-1 14q24.3
FOSB FosB proto-oncogene, AP-1 transcription factor subunit G0S3, GOSB, GOS3, AP-1, MGC42291, DKFZp686C0818 19q13.32
FOSL1 FOS like 1, AP-1 transcription factor subunit fra-1 11q13.1
FOSL2 FOS like 2, AP-1 transcription factor subunit FRA2, FLJ23306 2p23.2
JDP2 Jun dimerization protein 2 JUNDM2 14q24.3
JUN Jun proto-oncogene, AP-1 transcription factor subunit c-Jun, AP-1 1p32.1
JUNB JunB proto-oncogene, AP-1 transcription factor subunit 19p13.13
JUND JunD proto-oncogene, AP-1 transcription factor subunit AP-1 19p13.11
MAF MAF bZIP transcription factor c-MAF 16q23.2
MAFA MAF bZIP transcription factor A RIPE3b1, hMafA 8q24.3
MAFB MAF bZIP transcription factor B KRML 20q12
MAFF MAF bZIP transcription factor F hMafF 22q13.1
MAFG MAF bZIP transcription factor G MGC13090, MGC20149 17q25.3
MAFK MAF bZIP transcription factor K P18, NFE2U 7p22.3
NFE2 nuclear factor, erythroid 2 NF-E2 12q13
NFE2L1 nuclear factor, erythroid 2 like 1 TCF11 NRF1, LCR-F1, FLJ00380 17q21.3
NFE2L2 nuclear factor, erythroid 2 like 2 NRF2 2q31.2
NFE2L3 nuclear factor, erythroid 2 like 3 Nrf3 7p15.2
NFIL3 nuclear factor, interleukin 3 regulated IL3BP1 E4BP4, NFIL3A, NF-IL3A 9q22.31
NRL neural retina leucine zipper D14S46E, RP27, NRL-MAF 14q11.2-q12
XBP1 X-box binding protein 1 XBP2 22q12.1

Genes contained within subsets