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Gene Family: Lysine methyltransferases (KMT)

Also known as : "Lysine (K)-specific methyltransferases"

Genes contained within the family: 34

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
SUV39H1 suppressor of variegation 3-9 homolog 1 SUV39H KMT1A Xp11.23
SUV39H2 suppressor of variegation 3-9 homolog 2 FLJ23414, KMT1B 10p13
EHMT2 euchromatic histone lysine methyltransferase 2 C6orf30, BAT8 KMT1C, NG36/G9a, G9A, Em:AF134726.3 6p21.33
EHMT1 euchromatic histone lysine methyltransferase 1 EHMT1-IT1 FLJ40292, KIAA1876, bA188C12.1, KMT1D, FLJ12879, Eu-HMTase1 9q34.3
SETDB1 SET domain bifurcated 1 ESET, KIAA0067, KG1T, KMT1E, TDRD21 1q21.3
SETDB2 SET domain bifurcated 2 C13orf4 KMT1F, CLLL8, CLLD8 13q14.2
KMT2A lysine methyltransferase 2A MLL TRX1, HRX, ALL-1, HTRX1, CXXC7, MLL1A 11q23.3
KMT2B lysine methyltransferase 2B KIAA0304, MLL2, TRX2, HRX2, WBP7, MLL1B, MLL4, CXXC10 19q13.12
KMT2C lysine methyltransferase 2C MLL3 KIAA1506, HALR 7q36.1
KMT2D lysine methyltransferase 2D TNRC21, MLL2 ALR, MLL4, CAGL114 12q13.12
KMT2E lysine methyltransferase 2E MLL5 HDCMC04P 7q22.3
SETD1A SET domain containing 1A KMT2F, KIAA0339, Set1 16p11.2
SETD1B SET domain containing 1B Set1B, KIAA1076, KMT2G 12q24.31
ASH1L ASH1 like histone lysine methyltransferase huASH1, ASH1, KMT2H, ASH1L1 1q22
SETD2 SET domain containing 2 FLJ23184, KMT3A, KIAA1732, HYPB, HIF-1 3p21.31
NSD1 nuclear receptor binding SET domain protein 1 STO FLJ22263, ARA267, KMT3B 5q35.3
SMYD2 SET and MYND domain containing 2 ZMYND14, HSKM-B, KMT3C 1q32.3
SMYD1 SET and MYND domain containing 1 ZMYND22, KMT3D, BOP 2p11.2
SMYD3 SET and MYND domain containing 3 ZNFN3A1, ZMYND1 KMT3E 1q44
NSD3 nuclear receptor binding SET domain protein 3 WHSC1L1 KMT3F, WHISTLE, FLJ20353 8p11.23
NSD2 nuclear receptor binding SET domain protein 2 WHSC1 KMT3G, MMSET 4p16.3
DOT1L DOT1 like histone lysine methyltransferase DOT1, KMT4, KIAA1814 19p13.3
KMT5A lysine methyltransferase 5A SETD8 SET8, SET07, PR-Set7 12q24.31
KMT5B lysine methyltransferase 5B SUV420H1 CGI-85 11q13.2
KMT5C lysine methyltransferase 5C SUV420H2 MGC2705 19q13.42
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit ENX-1, EZH1, KMT6A, KMT6 7q36.1
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit KMT6B, KIAA0388 17q21.2
SETD7 SET domain containing lysine methyltransferase 7 KMT7, SET7, SET7/9, Set9, KIAA1717 4q31.1
PRDM2 PR/SET domain 2 KMT8, HUMHOXY1, KMT8A, RIZ1, RIZ2, MTB-ZF, RIZ 1p36.21
PRDM9 PR/SET domain 9 MSBP3 PFM6, ZNF899, KMT8B 5p14.2
PRDM6 PR/SET domain 6 PRISM, KMT8C 5q23.2
PRDM8 PR/SET domain 8 KMT8D 4q21.21
MECOM MDS1 and EVI1 complex locus MDS1, EVI1 PRDM3, MDS1-EVI1, KMT8E 3q26.2
PRDM16 PR/SET domain 16 MGC166915, KMT8F, KIAA1675, PFM13, MEL1 1p36.32

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