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Gene Family: Beta-1,3-glucuronyltransferases (B3GAT)

Also known as : "Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferases", "Glucuronosyltransferases, type I", "Uridine diphosphate glucuronic acid:acceptor glucuronosyltransferases"
A subset of : Glycosyltransferases

Beta-1,3-glucuronyltransferases: Beta-1,3-glucuronyltransferases (EC 2.4.1.135) catalyse the following reaction: UDP-glucuronate + 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein <=> UDP + 3-beta-D-glucuronosyl-3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein. [Source: HGNC]

Genes contained within the family: 3

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
B3GAT1 beta-1,3-glucuronyltransferase 1 CD57, LEU7 GlcAT-P, HNK-1, NK-1 11q25
B3GAT2 beta-1,3-glucuronyltransferase 2 GlcAT-S 6q13
B3GAT3 beta-1,3-glucuronyltransferase 3 GlcAT-I 11q12.3

Comments

These genes belong to GlycosylTransferase Family 43 in the CAZy enzyme classification scheme.