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Gene Family: Immunoglobulin heavy locus at 14q32.33 (IGH)

A subset of : Immunoglobulin heavy

IGH locus: The IGH locus is at 14q32.33 and contains IGHV (variable) genes, IGHD (diversity) genes, IGHJ (joining) genes, and IGHA, IGHG, IGHD, IGHE and IGHM constant genes. [Source: HGNC]

Genes contained within the family: 187

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
IGH immunoglobulin heavy locus IGHDY1, IGH@ 14q32.33
IGHV1-2 immunoglobulin heavy variable 1-2 V35 14q32.33
IGHV1-3 immunoglobulin heavy variable 1-3 VI-3B 14q32.33
IGHV1-12 immunoglobulin heavy variable 1-12 (pseudogene) 14q32.33
IGHV1-8 immunoglobulin heavy variable 1-8 14q32.33 not on reference assembly
IGHV1-14 immunoglobulin heavy variable 1-14 (pseudogene) 14q32.33
IGHV1-17 immunoglobulin heavy variable 1-17 (pseudogene) 14q32.33
IGHV1-18 immunoglobulin heavy variable 1-18 14q32.33
IGHV1-24 immunoglobulin heavy variable 1-24 14q32.33
IGHV1-45 immunoglobulin heavy variable 1-45 14q32.33
IGHV1-46 immunoglobulin heavy variable 1-46 14q32.33
IGHV1-58 immunoglobulin heavy variable 1-58 14q32.33
IGHV1-67 immunoglobulin heavy variable 1-67 (pseudogene) 14q32.33
IGHV1-68 immunoglobulin heavy variable 1-68 (pseudogene) 14q32.33
IGHV1-69 immunoglobulin heavy variable 1-69 IGHV1-E 14q32.33
IGHV1-69D immunoglobulin heavy variable 1-69D 14q32.33
IGHV1-38-4 immunoglobulin heavy variable 1-38-4 (non-functional) IGHV1-C IGHV1-c 14q32.33 not on reference assembly
IGHV1-69-2 immunoglobulin heavy variable 1-69-2 IGHV1-F IGHV1-f 14q32.33
IGHV2-5 immunoglobulin heavy variable 2-5 14q32.33
IGHV2-10 immunoglobulin heavy variable 2-10 (pseudogene) 14q32.33 not on reference assembly
IGHV2-26 immunoglobulin heavy variable 2-26 14q32.33
IGHV2-70 immunoglobulin heavy variable 2-70 14q32.33
IGHV2-70D immunoglobulin heavy variable 2-70D 14q32.33
IGHV3-6 immunoglobulin heavy variable 3-6 (pseudogene) 14q32.33
IGHV3-7 immunoglobulin heavy variable 3-7 14q32.33
IGHV3-9 immunoglobulin heavy variable 3-9 14q32.33
IGHV3-11 immunoglobulin heavy variable 3-11 (gene/pseudogene) 14q32.33
IGHV3-13 immunoglobulin heavy variable 3-13 14q32.33
IGHV3-15 immunoglobulin heavy variable 3-15 14q32.33
IGHV3-16 immunoglobulin heavy variable 3-16 (non-functional) 14q32.33
IGHV3-19 immunoglobulin heavy variable 3-19 (pseudogene) 14q32.33
IGHV3-20 immunoglobulin heavy variable 3-20 14q32.33
IGHV3-21 immunoglobulin heavy variable 3-21 14q32.33
IGHV3-22 immunoglobulin heavy variable 3-22 (pseudogene) 14q32.33
IGHV3-23 immunoglobulin heavy variable 3-23 14q32.33
IGHV3-25 immunoglobulin heavy variable 3-25 (pseudogene) 14q32.33
IGHV3-29 immunoglobulin heavy variable 3-29 (pseudogene) 14q32.33
IGHV3-30 immunoglobulin heavy variable 3-30 14q32.33
IGHV3-30-2 immunoglobulin heavy variable 3-30-2 (pseudogene) 14q32.33
IGHV3-30-3 immunoglobulin heavy variable 3-30-3 14q32.33 not on reference assembly
IGHV3-30-5 immunoglobulin heavy variable 3-30-5 14q32.33 not on reference assembly
IGHV3-32 immunoglobulin heavy variable 3-32 (pseudogene) 14q32.33
IGHV3-33 immunoglobulin heavy variable 3-33 14q32.33
IGHV3-33-2 immunoglobulin heavy variable 3-33-2 (pseudogene) 14q32.33
IGHV3-35 immunoglobulin heavy variable 3-35 (non-functional) 14q32.33
IGHV3-36 immunoglobulin heavy variable 3-36 (pseudogene) 14q32.33
IGHV3-37 immunoglobulin heavy variable 3-37 (pseudogene) 14q32.33
IGHV3-38 immunoglobulin heavy variable 3-38 (non-functional) 14q32.33
IGHV3-41 immunoglobulin heavy variable 3-41 (pseudogene) 14q32.33
IGHV3-42 immunoglobulin heavy variable 3-42 (pseudogene) 14q32.33
IGHV3-43 immunoglobulin heavy variable 3-43 14q32.33
IGHV3-43D immunoglobulin heavy variable 3-43D 14q32.33 not on reference assembly
IGHV3-47 immunoglobulin heavy variable 3-47 (pseudogene) 14q32.33
IGHV3-48 immunoglobulin heavy variable 3-48 14q32.33
IGHV3-49 immunoglobulin heavy variable 3-49 14q32.33
IGHV3-50 immunoglobulin heavy variable 3-50 (pseudogene) 14q32.33
IGHV3-52 immunoglobulin heavy variable 3-52 (pseudogene) 14q32.33
IGHV3-53 immunoglobulin heavy variable 3-53 14q32.33
IGHV3-54 immunoglobulin heavy variable 3-54 (pseudogene) 14q32.33
IGHV3-57 immunoglobulin heavy variable 3-57 (pseudogene) 14q32.33
IGHV3-60 immunoglobulin heavy variable 3-60 (pseudogene) 14q32.33
IGHV3-62 immunoglobulin heavy variable 3-62 (pseudogene) 14q32.33
IGHV3-63 immunoglobulin heavy variable 3-63 (pseudogene) 14q32.33
IGHV3-64 immunoglobulin heavy variable 3-64 14q32.33
IGHV3-65 immunoglobulin heavy variable 3-65 (pseudogene) 14q32.33
IGHV3-66 immunoglobulin heavy variable 3-66 14q32.33
IGHV3-71 immunoglobulin heavy variable 3-71 (pseudogene) IGHV3-G IGHV3-g 14q32.33
IGHV3-72 immunoglobulin heavy variable 3-72 14q32.33
IGHV3-73 immunoglobulin heavy variable 3-73 14q32.33
IGHV3-74 immunoglobulin heavy variable 3-74 14q32.33
IGHV3-75 immunoglobulin heavy variable 3-75 (pseudogene) 14q32.33
IGHV3-76 immunoglobulin heavy variable 3-76 (pseudogene) 14q32.33
IGHV3-79 immunoglobulin heavy variable 3-79 (pseudogene) 14q32.33
IGHV3-38-3 immunoglobulin heavy variable 3-38-3 (non-functional) IGHV3-D IGHV3-d 14q32.33 not on reference assembly
IGHV3-69-1 immunoglobulin heavy variable 3-69-1 (pseudogene) IGHV3-H IGHV3-h 14q32.33
IGHV4-4 immunoglobulin heavy variable 4-4 14q32.33
IGHV4-28 immunoglobulin heavy variable 4-28 14q32.33
IGHV4-30-1 immunoglobulin heavy variable 4-30-1 14q32.33
IGHV4-30-2 immunoglobulin heavy variable 4-30-2 IGHV4-3, IGHV4302 14q32.33
IGHV4-30-4 immunoglobulin heavy variable 4-30-4 IGHV4-3, IGHV4304 14q32.33 not on reference assembly
IGHV4-31 immunoglobulin heavy variable 4-31 14q32.33 not on reference assembly
IGHV4-34 immunoglobulin heavy variable 4-34 14q32.33
IGHV4-39 immunoglobulin heavy variable 4-39 14q32.33
IGHV4-55 immunoglobulin heavy variable 4-55 (pseudogene) 14q32.33
IGHV4-59 immunoglobulin heavy variable 4-59 14q32.33
IGHV4-61 immunoglobulin heavy variable 4-61 14q32.33
IGHV4-80 immunoglobulin heavy variable 4-80 (pseudogene) 14q32.33
IGHV4-38-2 immunoglobulin heavy variable 4-38-2 IGHV4-B 14q32.33 not on reference assembly
IGHV5-51 immunoglobulin heavy variable 5-51 14q32.33
IGHV5-78 immunoglobulin heavy variable 5-78 (pseudogene) 14q32.33
IGHV5-10-1 immunoglobulin heavy variable 5-10-1 IGHV5-A IGHV5-a 14q32.33
IGHV6-1 immunoglobulin heavy variable 6-1 14q32.33
IGHV7-4-1 immunoglobulin heavy variable 7-4-1 14q32.33
IGHV7-40 immunoglobulin heavy variable 7-40 (pseudogene) 14q32.33
IGHV7-27 immunoglobulin heavy variable 7-27 (pseudogene) 14q32.33
IGHV7-56 immunoglobulin heavy variable 7-56 (pseudogene) 14q32.33
IGHV7-34-1 immunoglobulin heavy variable 7-34-1 (pseudogene) 14q32.33
IGHV7-81 immunoglobulin heavy variable 7-81 (non-functional) 14q32.33
IGHVII-1-1 immunoglobulin heavy variable (II)-1-1 (pseudogene) IGHV(II)-1-1 14q32.33
IGHVII-15-1 immunoglobulin heavy variable (II)-15-1 (pseudogene) IGHV(II)-15-1 14q32.33
IGHVII-20-1 immunoglobulin heavy variable (II)-20-1 (pseudogene) IGHV(II)-20-1 14q32.33
IGHVII-22-1 immunoglobulin heavy variable (II)-22-1 (pseudogene) IGHV(II)-22-1 14q32.33
IGHVII-26-2 immunoglobulin heavy variable (II)-26-2 (pseudogene) IGHV(II)-26-2 14q32.33
IGHVII-28-1 immunoglobulin heavy variable (II)-28-1 (pseudogene) IGHV(II)-28-1 14q32.33
IGHVII-30-1 immunoglobulin heavy variable (II)-30-1 (pseudogene) IGHV(II)-30-1 14q32.33
IGHVII-30-21 immunoglobulin heavy variable (II)-30-21 (pseudogene) IGHV(II)-30-21 14q32.33
IGHVII-31-1 immunoglobulin heavy variable (II)-31-1 (pseudogene) IGHV(II)-31-1 14q32.33 not on reference assembly
IGHVII-33-1 immunoglobulin heavy variable (II)-33-1 (pseudogene) IGHV(II)-33-1 14q32.33
IGHVII-40-1 immunoglobulin heavy variable (II)-40-1 (pseudogene) IGHV(II)-40-1 14q32.33
IGHVII-43-1 immunoglobulin heavy variable (II)-43-1 (pseudogene) IGHV(II)-43-1 14q32.33
IGHVII-44-2 immunoglobulin heavy variable (II)-44-2 (pseudogene) IGHV(II)-44-2 14q32.33
IGHVII-46-1 immunoglobulin heavy variable (II)-46-1 (pseudogene) IGHV(II)-46-1 14q32.33
IGHVII-49-1 immunoglobulin heavy variable (II)-49-1 (pseudogene) IGHV(II)-49-1 14q32.33
IGHVII-51-2 immunoglobulin heavy variable (II)-51-2 (pseudogene) IGHV(II)-51-2 14q32.33
IGHVII-53-1 immunoglobulin heavy variable (II)-53-1 (pseudogene) IGHV(II)-53-1 14q32.33
IGHVII-60-1 immunoglobulin heavy variable (II)-60-1 (pseudogene) IGHV(II)-60-1 14q32.33
IGHVII-62-1 immunoglobulin heavy variable (II)-62-1 (pseudogene) IGHV(II)-62-1 14q32.33
IGHVII-65-1 immunoglobulin heavy variable (II)-65-1 (pseudogene) IGHV(II)-65-1 14q32.33
IGHVII-67-1 immunoglobulin heavy variable (II)-67-1 (pseudogene) IGHV(II)-67-1 14q32.33
IGHVII-74-1 immunoglobulin heavy variable (II)-74-1 (pseudogene) IGHV(II)-74-1 14q32.33
IGHVII-78-1 immunoglobulin heavy variable (II)-78-1 (pseudogene) IGHV(II)-78-1 14q32.33
IGHVIII-2-1 immunoglobulin heavy variable (III)-2-1 (pseudogene) IGHV(III)-2-1 14q32.33
IGHVIII-5-1 immunoglobulin heavy variable (III)-5-1 (pseudogene) IGHV(III)-5-1 14q32.33
IGHVIII-5-2 immunoglobulin heavy variable (III)-5-2 (pseudogene) IGHV(III)-5-2 14q32.33
IGHVIII-11-1 immunoglobulin heavy variable (III)-11-1 (pseudogene) IGHV(III)-11-1 14q32.33
IGHVIII-13-1 immunoglobulin heavy variable (III)-13-1 (pseudogene) IGHV(III)-13-1 14q32.33
IGHVIII-16-1 immunoglobulin heavy variable (III)-16-1 (pseudogene) IGHV(III)-16-1 14q32.33
IGHVIII-22-2 immunoglobulin heavy variable (III)-22-2 (pseudogene) IGHV(III)-22-2 14q32.33
IGHVIII-25-1 immunoglobulin heavy variable (III)-25-1 (pseudogene) IGHV(III)-25-1 14q32.33
IGHVIII-26-1 immunoglobulin heavy variable (III)-26-1 (pseudogene) IGHV(III)-26-1 14q32.33
IGHVIII-38-1 immunoglobulin heavy variable (III)-38-1 (pseudogene) IGHV(III)-38-1 14q32.33
IGHVIII-44 immunoglobulin heavy variable (III)-44 (pseudogene) IGHV(III)-44 14q32.33
IGHVIII-47-1 immunoglobulin heavy variable (III)-47-1 (pseudogene) IGHV(III)-47-1 14q32.33
IGHVIII-51-1 immunoglobulin heavy variable (III)-51-1 (pseudogene) IGHV(III)-51-1 14q32.33
IGHVIII-67-2 immunoglobulin heavy variable (III)-67-2 (pseudogene) IGHV(III)-67-2 14q32.33
IGHVIII-67-3 immunoglobulin heavy variable (III)-67-3 (pseudogene) IGHV(III)-67-3 14q32.33
IGHVIII-67-4 immunoglobulin heavy variable (III)-67-4 (pseudogene) IGHV(III)-67-4 14q32.33
IGHVIII-76-1 immunoglobulin heavy variable (III)-76-1 (pseudogene) IGHV(III)-76-1 14q32.33
IGHVIII-82 immunoglobulin heavy variable (III)-82 (pseudogene) IGHV(III)-82 14q32.33
IGHVIV-44-1 immunoglobulin heavy variable (IV)-44-1 (pseudogene) IGHV(IV)-44-1 14q32.33
IGHD1-1 immunoglobulin heavy diversity 1-1 IGHD11 14q32.33
IGHD1-7 immunoglobulin heavy diversity 1-7 DM1, IGHD17 14q32.33
IGHD1-14 immunoglobulin heavy diversity 1-14 (non-functional) IGHD114, DM2 14q32.33
IGHD1-20 immunoglobulin heavy diversity 1-20 IGHD120 14q32.33
IGHD1-26 immunoglobulin heavy diversity 1-26 IGHD126 14q32.33
IGHD2-2 immunoglobulin heavy diversity 2-2 IGHD22 14q32.33
IGHD2-8 immunoglobulin heavy diversity 2-8 IGHD28, DLR1 14q32.33
IGHD2-15 immunoglobulin heavy diversity 2-15 IGHD215, D2 14q32.33
IGHD2-21 immunoglobulin heavy diversity 2-21 IGHD221 14q32.33
IGHD3-3 immunoglobulin heavy diversity 3-3 IGHD33, DXP4 14q32.33
IGHD3-9 immunoglobulin heavy diversity 3-9 IGHD39, DXP1 14q32.33
IGHD3-10 immunoglobulin heavy diversity 3-10 IGHD310, DXP'1 14q32.33
IGHD3-16 immunoglobulin heavy diversity 3-16 IGHD316 14q32.33
IGHD3-22 immunoglobulin heavy diversity 3-22 IGHD322 14q32.33
IGHD4-4 immunoglobulin heavy diversity 4-4 IGHD44, DA4 14q32.33
IGHD4-11 immunoglobulin heavy diversity 4-11 (non-functional) IGHD411, DA1 14q32.33
IGHD4-17 immunoglobulin heavy diversity 4-17 IGHD417 14q32.33
IGHD4-23 immunoglobulin heavy diversity 4-23 (non-functional) IGHD423 14q32.33
IGHD5-5 immunoglobulin heavy diversity 5-5 IGHD55, DK4 14q32.33
IGHD5-12 immunoglobulin heavy diversity 5-12 IGHD512, DK1 14q32.33
IGHD5-18 immunoglobulin heavy diversity 5-18 IGHD518 14q32.33
IGHD5-24 immunoglobulin heavy diversity 5-24 (non-functional) IGHD524 14q32.33
IGHD6-6 immunoglobulin heavy diversity 6-6 IGHD66, D(N4) 14q32.33
IGHD6-13 immunoglobulin heavy diversity 6-13 IGHD613, DN1 14q32.33
IGHD6-19 immunoglobulin heavy diversity 6-19 IGHD619 14q32.33
IGHD6-25 immunoglobulin heavy diversity 6-25 IGHD625 14q32.33
IGHD7-27 immunoglobulin heavy diversity 7-27 IGHD727, DHQ52 14q32.33
IGHJ1 immunoglobulin heavy joining 1 14q32.33
IGHJ1P immunoglobulin heavy joining 1P (pseudogene) Jpsi1 14q32.33
IGHJ2 immunoglobulin heavy joining 2 14q32.33
IGHJ2P immunoglobulin heavy joining 2P (pseudogene) Jpsi2 14q32.33
IGHJ3 immunoglobulin heavy joining 3 14q32.33
IGHJ3P immunoglobulin heavy joining 3P (pseudogene) Jpsi3 14q32.33
IGHJ4 immunoglobulin heavy joining 4 14q32.33
IGHJ5 immunoglobulin heavy joining 5 14q32.33
IGHJ6 immunoglobulin heavy joining 6 14q32.33
IGHA1 immunoglobulin heavy constant alpha 1 14q32.33
IGHA2 immunoglobulin heavy constant alpha 2 (A2m marker) 14q32.33
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker) 14q32.33
IGHG2 immunoglobulin heavy constant gamma 2 (G2m marker) 14q32.33
IGHG3 immunoglobulin heavy constant gamma 3 (G3m marker) 14q32.33
IGHG4 immunoglobulin heavy constant gamma 4 (G4m marker) 14q32.33
IGHGP immunoglobulin heavy constant gamma P (non-functional) IGHGP1 14q32.33
IGHD immunoglobulin heavy constant delta FLJ00382, FLJ46727, MGC29633 14q32.33
IGHE immunoglobulin heavy constant epsilon 14q32.33
IGHEP1 immunoglobulin heavy constant epsilon P1 (pseudogene) 14q32.33
IGHM immunoglobulin heavy constant mu 14q32.33

Comments

For further reading, please see: Lefranc M.-P. and Lefranc G. The Immunoglobulin FactsBook, Academic Press, 2001

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