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Gene Family: Glutamate metabotropic receptors (GRM)

Also known as : "mGluR", "Metabotropic glutamate receptors", "Glutamate receptors, metabotropic"

Metabotropic glutamate receptor: The metabotropic glutamate receptors, or mGluR s, are a type of glutamate receptor that are active through an indirect metabotropic process. They are members of the group C family of G-protein-coupled receptors, or GPCRs. Like all glutamate receptors, mGluRs bind with glutamate, an amino acid that functions as an excitatory neurotransmitter. [Source: Wikipedia]

Genes contained within the family: 8

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
GRM1 glutamate metabotropic receptor 1 GPRC1A, mGlu1, MGLUR1, PPP1R85 6q24.3
GRM2 glutamate metabotropic receptor 2 GPRC1B, mGlu2, MGLUR2 3p21.2
GRM3 glutamate metabotropic receptor 3 GPRC1C, mGlu3, MGLUR3 7q21.11-q21.12
GRM4 glutamate metabotropic receptor 4 GPRC1D, mGlu4, MGLUR4 6p21.31
GRM5 glutamate metabotropic receptor 5 MGLUR5, GPRC1E, mGlu5, PPP1R86 11q14.2-q14.3
GRM6 glutamate metabotropic receptor 6 GPRC1F, mGlu6, MGLUR6, CSNB1B 5q35.3
GRM7 glutamate metabotropic receptor 7 GLUR7, GPRC1G, mGlu7, MGLUR7, PPP1R87 3p26.1
GRM8 glutamate metabotropic receptor 8 GLUR8, GPRC1H, mGlu8, MGLUR8 7q31.33