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Gene Family: Gamma-aminobutyric acid type B receptor subunits (GABBR)

Also known as : "GABA(B) receptors", "GABA BRs", "Gamma-aminobutyric acid (GABA) B receptors"

GABAB receptor: GABA B receptors (GABA BR) are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA) that are linked via G-proteins to potassium channels. The changing potassium concentrations hyperpolarize the cell at the end of an action potential. The reversal potential the GABA B-mediated IPSP is -100 mV, which is much more hyperpolarized than the GABA A IPSP. GABA B receptors are found in the central and peripheral autonomic nervous system. [Source: Wikipedia]

Genes contained within the family: 2

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
GABBR1 gamma-aminobutyric acid type B receptor subunit 1 hGB1a, GPRC3A 6p22.1
GABBR2 gamma-aminobutyric acid type B receptor subunit 2 GPR51 HG20, GABABR2, GPRC3B 9q22.33