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Gene Family: F2R receptors (F2R)

Also known as : "Protease-activated receptors", "PARs", "Proteinase-activated receptors", "Coagulation factor II (thrombin) receptors"

Protease-activated receptor: Protease-activated receptor s are a subfamily of related G protein-coupled receptors that are activated by cleavage of part of their extracellular domain. They are highly expressed in platelets, but also on endothelial cells, myocytes and neurons. [Source: Wikipedia]

Genes contained within the family: 4

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
F2R coagulation factor II thrombin receptor TR, CF2R, PAR1, PAR-1 5q13.3
F2RL1 F2R like trypsin receptor 1 GPR11 PAR2 5q13.3
F2RL2 coagulation factor II thrombin receptor like 2 PAR3 5q13.3
F2RL3 F2R like thrombin or trypsin receptor 3 PAR4 19p13.11