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Gene Family: Formyl peptide receptors (FPR)

Formyl peptide receptor: The formyl peptide receptors (FPR) belong to a class of G protein-coupled receptors involved in chemotaxis. These receptors were originally identified by their ability to bind N-formyl peptides such as N -formylmethionine produced by the degradation of either bacterial or host cells. Hence formyl peptide receptors are involved in mediating immune cell response to infection. These receptors may also act to suppress the immune system under certain conditions. The close phylogenetical relation of signaling in chemotaxis and olfaction was recently proved by detection formyl peptide receptor like proteins as a distinct family of vomeronasal organ chemosensors in mice [Source: Wikipedia]

Genes contained within the family: 3

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
FPR1 formyl peptide receptor 1 FPR, FMLP 19q13.41
FPR2 formyl peptide receptor 2 FPRL1 LXA4R, HM63, FPRH2, FMLPX, FPR2A, FMLP-R-II, ALXR 19q13.41
FPR3 formyl peptide receptor 3 FPRL2 FPRH1, FMLPY, RMLP-R-I 19q13.41