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Gene Family: DOCK C2 domain containing (DOCK)

Also known as : "C2 domain containing DOCK and Zizimin proteins"
A subset of : C2 domain containing

DOCK C2 domain containing:: This family of proteins plays a role in the regulation of Rho family small GTPases (Rac, Rho and Cdc42). Together the Rho family of small GTPases and the Dock/Zizimin proteins play a vital role in a number of cell processes including cell migration, apoptosis, cell division and cell adhesion. [Source: Pakes et al, 2013]

Genes contained within the family: 11

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
DOCK1 dedicator of cytokinesis 1 DOCK180, ced5 10q26.2
DOCK2 dedicator of cytokinesis 2 KIAA0209 5q35.1
DOCK3 dedicator of cytokinesis 3 KIAA0299, MOCA, PBP 3p21.2
DOCK4 dedicator of cytokinesis 4 FLJ34238, KIAA0716 7q31.1
DOCK5 dedicator of cytokinesis 5 FLJ21034 8p21.2
DOCK6 dedicator of cytokinesis 6 KIAA1395, ZIR1 19p13.2
DOCK7 dedicator of cytokinesis 7 KIAA1771, ZIR2 1p31.3
DOCK8 dedicator of cytokinesis 8 FLJ00026, FLJ00152, ZIR8, FLJ00346 9p24.3
DOCK9 dedicator of cytokinesis 9 KIAA1058, ZIZ1 13q32.3
DOCK10 dedicator of cytokinesis 10 ZIZ3, KIAA0694 2q36.2
DOCK11 dedicator of cytokinesis 11 FLJ32122, FLJ43653, ZIZ2, ACG Xq24

Publications

20713135,23247359,25022758