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Gene Family: M16 metallopeptidases

M16 metallopeptidases: These genes encode zinc dependent metallopeptidases in which two of the zinc ligands are histidines in a 'HXXEH' motif. [Source: MEROPS, Rawlings et al]

Genes contained within the family: 7

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
IDE insulin degrading enzyme 10q23.33
NRDC nardilysin convertase NRD1 hNRD1, hNRD2 1p32.3
PITRM1 pitrilysin metallopeptidase 1 MP1, KIAA1104, hMP1, PreP 10p15.2
PMPCA peptidase, mitochondrial processing alpha subunit INPP5E KIAA0123, Alpha-MPP 9q34.3
PMPCB peptidase, mitochondrial processing beta subunit MPPB, MPPP52 7q22.1
UQCRC1 ubiquinol-cytochrome c reductase core protein 1 D3S3191, QCR1, UQCR1 3p21.31
UQCRC2 ubiquinol-cytochrome c reductase core protein 2 QCR2, UQCR2 16p12.2

Comments

PLEASE NOTE: THIS GENE FAMILY HAS NOT BEEN REVIEWED BY OUR SCIENTIFIC EXPERT ADVISORS YET

External resources

Publications

22294699,27930980