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Gene Family: G protein subunits alpha, group i (GNAI)

Also known as : "Galphai subunits", "Gi proteins", "G inhibitory subunits", "Gi alpha subunits", "G-protein alpha subunits, group I", "G(I)alpha subunits", "Galphai/o subunits"

G-protein alpha subunit, group I: This family consists of the G protein alpha subunit group I (inhibitory), which includes G alpha-I, G alpha-O, G alpha-T and G alpha-Z. G alpha-I proteins were originally identified by their receptor-mediated inhibition of the cAMP-generating enzyme adenylyl cyclase. [Source: InterPro IPR001408]

Genes contained within the family: 8

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
GNAI1 G protein subunit alpha i1 7q21.11
GNAI2 G protein subunit alpha i2 GNAI2B GIP 3p21.31
GNAI3 G protein subunit alpha i3 87U6 1p13.3
GNAO1 G protein subunit alpha o1 G-ALPHA-o 16q13
GNAT1 G protein subunit alpha transducin 1 CSNBAD3 3p21.31
GNAT2 G protein subunit alpha transducin 2 ACHM4 1p13.3
GNAT3 G protein subunit alpha transducin 3 gustducin, GDCA 7q21.11
GNAZ G protein subunit alpha z 22q11.22-q11.23