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Gene Family: MINDY deubiquitinases (MINDY)

Also known as : "motif interacting with Ub-containing novel DUB family"

MINDY deubiquitinases: MINDY family DUBs are highly selective at cleaving K48-linked polyUb, a signal that targets proteins for degradation. [Source: https://www.ncbi.nlm.nih.gov/pubmed/27292798]

Genes contained within the family: 5

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
MINDY1 MINDY lysine 48 deubiquitinase 1 FAM63A FLJ11280, MINDY-1 1q21.3
MINDY2 MINDY lysine 48 deubiquitinase 2 FAM63B KIAA1164 15q21.3-q22.1
MINDY3 MINDY lysine 48 deubiquitinase 3 C10orf97, FAM188A FLJ13397, CARP, my042, DERP5 10p13
MINDY4 MINDY lysine 48 deubiquitinase 4 C7orf67, FAM188B FLJ22374 7p14.3
MINDY4B MINDY family member 4B C3orf76, FAM188B2 3q25.1

Publications

27292798,28082312