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Gene Family: Integrator complex (INTS)

Integrator complex: The Integrator complex associates with phosphorylated RNA polymerase II (RNAPII). This complex processes the 3′ end of the U-rich small nuclear RNA (snRNA). [Source: Baillat et al, 2015]

Genes contained within the family: 15

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
INTS1 integrator complex subunit 1 DKFZp586J0619, KIAA1440, INT1, NET28 7p22.3
INTS2 integrator complex subunit 2 KIAA1287 INT2 17q23.2
INTS3 integrator complex subunit 3 C1orf60 FLJ21919, INT3, SOSS-A 1q21.3
INTS4 integrator complex subunit 4 INT4, MGC16733, MST093 11q14.1
INTS5 integrator complex subunit 5 KIAA1698 INT5 11q12.3
INTS6 integrator complex subunit 6 DDX26 DICE1, HDB, Notchl2, DBI-1, DDX26A, INT6 13q14.3
INTS6L integrator complex subunit 6 like DDX26B FLJ41215 Xq26.3
INTS7 integrator complex subunit 7 C1orf73 DKFZP434B168, INT7 1q32.3
INTS8 integrator complex subunit 8 C8orf52 FLJ20530, INT8, MGC131633 8q22.1
INTS9 integrator complex subunit 9 FLJ10871, CPSF2L, RC-74 8p21.1
INTS10 integrator complex subunit 10 C8orf35 FLJ10569, INT10 8p21.3
INTS11 integrator complex subunit 11 CPSF3L FLJ20542, RC-68, CPSF73L, INT11 1p36.33
INTS12 integrator complex subunit 12 PHF22 SBBI22, INT12 4q24
INTS13 integrator complex subunit 13 C12orf11, ASUN FLJ10637, NET48, Mat89Bb, SPATA30 12p11.23
INTS14 integrator complex subunit 14 C15orf44, VWA9 DKFZP564O1664 15q22.31

Publications

27427483,25675981,25410209