Skip to Navigation

Gene Family: Cornified envelope precursor family

Cornified envelope precursor family: As it name implies, the cornified envelope (CE) precursor family includes genes that encode the proteins forming the CE. The CE is a cross-linked matrix that surrounds terminally differentiated squamous keratinocytes after a process known as cornification. CE precursor proteins are cross-linked by transglutaminases. The ratio of CE precursor proteins varies from tissue to tissue. In the epidermis, the most abundant CE component is loricrin (65-70%), while involucrin is a minor component (<5%). [Source: Wikipedia]

Genes contained within the family: 2

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
IVL involucrin 1q21.3
LOR loricrin 1q21.3

Publications

26778565,24648708,18166499