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Gene Family: BRCA1 B complex

BRCA1 B complex: The BRCA1-B complex is involved in DNA replication stress-induced checkpoint and DNA interstrand crosslink (ICL) repair [Source: Her et al, 2016]

Genes contained within the family: 4

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
BARD1 BRCA1 associated RING domain 1 2q35
BRCA1 BRCA1, DNA repair associated RNF53, BRCC1, PPP1R53, FANCS 17q21.31
BRIP1 BRCA1 interacting protein C-terminal helicase 1 OF, BACH1, FANCJ 17q23.2
TOPBP1 DNA topoisomerase II binding protein 1 KIAA0259, TOP2BP1 3q22.1

Publications

22369660,17664283,25483079