Skip to Navigation

Gene Family: 5FMC ribosome biogenesis complex

Also known as : "SENP3 associated protein complex", "LAS1L complex", "PELP1-TEX10-WDR18 complex", "Five Friends of Methylated Chtop complex"

5FMC ribosome biogenesis complex: This complex contains the mammalian homologs of the budding yeast Rix1 complex. It links arginine methylation to desumoylation and is important for ribosomal maturation. [Source: Fanis et al, 2012]

Genes contained within the family: 6

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
LAS1L LAS1 like, ribosome biogenesis factor FLJ12525 Xq12
NOL9 nucleolar protein 9 FLJ23323, NET6, Grc3 1p36.31
PELP1 proline, glutamate and leucine rich protein 1 MNAR 17p13.2
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 DKFZP586K0919, SSP3, DKFZp762A152, SMT3IP1, Ulp1 17p13
TEX10 testis expressed 10 FLJ20287, bA208F1.2, Ipi1 9q31.1
WDR18 WD repeat domain 18 Ipi3 19p13.3

Publications

22872859,22190735,21326211,22872859