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Gene Family: C-type lectin domain containing (CLEC)

C-type lectin: A C-type lectin (CLEC) is a type of carbohydrate-binding protein domain known as a lectin. The C-type designation is from their requirement for calcium for binding. Proteins that contain C-type lectin domains have a diverse range of functions including cell-cell adhesion, immune response to pathogens and apoptosis. [Source: Wikipedia]

Genes contained within the family: 86

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
ACAN aggrecan MSK16, CSPG1, AGC1 CSPGCP 15q26.1
ATRN attractin DPPT-L, MGCA 20p13
ATRNL1 attractin like 1 KIAA0534, FLJ45344, ALP 10q25.3
BCAN brevican BEHAB, MGC13038, CSPG7 1q23.1
CD72 CD72 molecule LYB2, CD72b 9p13.3
CD93 CD93 molecule MXRA4, C1QR1 C1qRP, C1qR(P), dJ737E23.1, CDw93, ECSM3 20p11.21
CD248 CD248 molecule CD164L1 TEM1 11q13.2
CHODL chondrolectin C21orf68 FLJ12627, PRED12, MT75 21q21.1
CLEC1A C-type lectin domain family 1 member A CLEC1, MGC34328 12p13.2
CLEC1B C-type lectin domain family 1 member B CLEC2 12p13.31-p13.2
CLEC2A C-type lectin domain family 2 member A UNQ5792, INPE5792, KACL, PILAR 12p13.31
CLEC2B C-type lectin domain family 2 member B CLECSF2 AICL, HP10085 12p13.31
CD69 CD69 molecule CLEC2C 12p13.31
CLEC2D C-type lectin domain family 2 member D LLT1, CLAX, OCIL 12p13.31
CLEC2L C-type lectin domain family 2 member L FLJ32986 7q34
CLEC3A C-type lectin domain family 3 member A CLECSF1 16q23.1
CLEC3B C-type lectin domain family 3 member B TNA TN 3p21.31
CLEC4A C-type lectin domain family 4 member A CLECSF6 DCIR, DDB27, CD367 12p13.31
CLEC4C C-type lectin domain family 4 member C CLECSF11, CLECSF7 HECL, DLEC, BDCA2, CD303 12p13.31
CLEC4D C-type lectin domain family 4 member D CLECSF8 Mpcl, CD368, MCL, Dectin-3 12p13.31
CLEC4E C-type lectin domain family 4 member E CLECSF9 mincle 12p13.31
CLEC4F C-type lectin domain family 4 member F CLECSF13 FLJ39110, KCLR 2p13.3
CLEC4G C-type lectin domain family 4 member G UNQ431, LSECtin 19p13.2
ASGR1 asialoglycoprotein receptor 1 CLEC4H1 17p13.1
ASGR2 asialoglycoprotein receptor 2 CLEC4H2 17p13.1
CD207 CD207 molecule CLEC4K, Langerin 2p13.3
CD209 CD209 molecule DC-SIGN1, DC-SIGN, CLEC4L, CDSIGN 19p13.2
CLEC5A C-type lectin domain containing 5A CLECSF5 MDL-1 7q34
CLEC6A C-type lectin domain containing 6A CLECSF10 dectin-2 12p13.31
CLEC7A C-type lectin domain containing 7A CLECSF12 dectin-1, hDectin-1, CD369, SCARE2 12p13.2
CLEC9A C-type lectin domain containing 9A UNQ9341, HEEE9341, CD370, DNGR-1 12p13.2
CLEC10A C-type lectin domain containing 10A CLECSF13, CLECSF14 HML2, HML, CD301 17p13.1
CLEC11A C-type lectin domain containing 11A SCGF P47, LSLCL, CLECSF3 19q13.33
CLEC12A C-type lectin domain family 12 member A CLL-1, MICL, CD371, DCAL-2 12p13.31
CLEC12B C-type lectin domain family 12 member B 12p13.2
CD302 CD302 molecule BIMLEC, KIAA0022, CLEC13A, DCL-1 2q24.2
CLEC14A C-type lectin domain containing 14A C14orf27 14q21.1
CLEC16A C-type lectin domain containing 16A KIAA0350 Gop-1 16p13.13
CLEC17A C-type lectin domain containing 17A FLJ45910 19p13.12
CLEC18A C-type lectin domain family 18 member A MRCL 16q22.1
CLEC18B C-type lectin domain family 18 member B MRCL2 16q23.1
CLEC18C C-type lectin domain family 18 member C MRCL3 MGC34761 16q22.1
CLEC19A C-type lectin domain containing 19A 16p12.3
CLEC20A C-type lectin domain containing 20A NCRNA00083, LINC00083 FLJ44005, RP4-593C16.2 1q25.2
COLEC10 collectin subfamily member 10 CL-L1 8q24.12
COLEC11 collectin subfamily member 11 MGC3279, CL-K1 2p25.3
COLEC12 collectin subfamily member 12 SRCL, CL-P1, SCARA4 18p11.32
DGCR2 DiGeorge syndrome critical region gene 2 KIAA0163, LAN, IDD, DGS-C, SEZ-12 22q11.21
FCER2 Fc fragment of IgE receptor II CD23A, FCE2 CLEC4J, CD23 19p13.2
FREM1 FRAS1 related extracellular matrix 1 C9orf154 FLJ25461, C9orf145, C9orf143, DKFZp686M16108, TILRR 9p22.3
KLRB1 killer cell lectin like receptor B1 NKR CD161, NKR-P1, NKR-P1A, hNKR-P1A, CLEC5B 12p13.31
KLRC1 killer cell lectin like receptor C1 NKG2 NKG2-A, NKG2-B, CD159a 12p13
KLRC2 killer cell lectin like receptor C2 NKG2-C, CD159c 12p13
KLRC3 killer cell lectin like receptor C3 NKG2-E 12p13.2
KLRD1 killer cell lectin like receptor D1 CD94 12p13
KLRF1 killer cell lectin like receptor F1 CLEC5C, NKp80 12p13.31
KLRF2 killer cell lectin like receptor F2 NKp65 12p13.31
KLRG1 killer cell lectin like receptor G1 MAFA, 2F1, MAFA-L, CLEC15A 12p13.31
KLRG2 killer cell lectin like receptor G2 FLJ44186, CLEC15B 7q34
KLRK1 killer cell lectin like receptor K1 D12S2489E NKG2D, KLR, NKG2-D, CD314 12p13.2
LAYN layilin FLJ30977, FLJ31092 11q23.1
LY75 lymphocyte antigen 75 DEC-205, CLEC13B, CD205 2q24.2
MBL1P mannose binding lectin 1, pseudogene MBL1P1 COLEC3P 10q22.3
MRC1 mannose receptor C-type 1 MRC1L1 CLEC13D, CD206, bA541I19.1, CLEC13DL 10p12.33
MRC2 mannose receptor C type 2 KIAA0709, ENDO180, CLEC13E, CD280 17q23
NCAN neurocan CSPG3 19p12
OLR1 oxidized low density lipoprotein receptor 1 LOX-1, SCARE1, CLEC8A 12p13.2
PKD1 polycystin 1, transient receptor potential channel interacting PBP, Pc-1, TRPP1 16p13.3
PKD1L2 polycystin 1 like 2 (gene/pseudogene) KIAA1879 16q23.2
PKD1L3 polycystin 1 like 3, transient receptor potential channel interacting 16q22.2
PLA2R1 phospholipase A2 receptor 1 PLA2G1R, PLA2IR, PLA2-R, CLEC13C 2q23-q24
PRG2 proteoglycan 2, pro eosinophil major basic protein MBP, BMPG, proMBP 11q12.1
PRG3 proteoglycan 3, pro eosinophil major basic protein 2 MBPH, MBP2 11q12.1
REG1A regenerating family member 1 alpha REG PSP, PTP, PSPS, PSPS1 2p12
REG1B regenerating family member 1 beta REGL, PSPS2, REGH, REGI-BETA 2p12
REG3A regenerating family member 3 alpha PAP HIP, REG-III, REG3, PBCGF, PAP1 2p12
REG3G regenerating family member 3 gamma UNQ429, LPPM429, PAP1B 2p12
REG4 regenerating family member 4 REG-IV, RELP, GISP 1p12
SELE selectin E ELAM1, ELAM ESEL, CD62E 1q24.2
SELL selectin L LYAM1, LNHR LSEL, LAM1, LAM-1, hLHRc, Leu-8, Lyam-1, PLNHR, CD62L 1q24.2
SELP selectin P GRMP CD62, PSEL, PADGEM, GMP140, CD62P 1q24.2
SFTPA1 surfactant protein A1 SFTP1 SP-A, SP-A1, COLEC4 10q22.3
SFTPA2 surfactant protein A2 SP-A2, COLEC5 10q22.3
SFTPD surfactant protein D SFTP4 SP-D, COLEC7 10q22.3
THBD thrombomodulin CD141 20p11.21
VCAN versican CSPG2 PG-M 5q14.2-q14.3