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Gene Family: Mannosidases alpha class 1 (MAN1)

Also known as : "Class 1 (Family 47 Glycosylhydrolase) alpha 1,2-Mannosidases", "Class I alpha mannosidases", "Class 1 alpha 1,2-mannosidases"

Class 1 alpha-mannosidases: Class 1 alpha-mannosidases recognize and cleave only alpha-1,2–linked mannose residues from the Man9GlcNAc2 high-mannose precursor. [Source: Mast & Moreman, 2006]

Genes contained within the family: 4

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
MAN1A1 mannosidase alpha class 1A member 1 6q22.31
MAN1A2 mannosidase alpha class 1A member 2 MAN1B 1p12
MAN1B1 mannosidase alpha class 1B member 1 MANA-ER, MRT15, ERManI 9q34.3
MAN1C1 mannosidase alpha class 1C member 1 HMIC 1p36.11

Publications

11673242,17116466