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Gene Family: Lysozymes, c-type (LYZ)

Also known as : "chicken-type lysozyme"
A subset of : Lysozymes

Lysozyme: Lysozymes, also known as muramidase or N-acetylmuramide glycanhydrolase, are glycoside hydrolases. These are enzymes ( EC 3.2.1.17 ) that damage bacterial cell walls by catalyzing hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. Lysozyme is abundant in a number of secretions, such as tears, saliva, human milk, and mucus. It is also present in cytoplasmic granules of the macrophages and the polymorphonuclear neutrophils (PMNs). Large amounts of lysozyme can be found in egg white. C-type lysozymes are closely related to alpha-lactalbumin in sequence and structure, making them part of the same family. In humans, the lysozyme enzyme is encoded by the LYZ gene. [Source: Wikipedia]

Genes contained within the family: 9

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
LYZ lysozyme 12q15
LYZL1 lysozyme like 1 MGC33408, LYC2 10p12.1-p11.23
LYZL2 lysozyme like 2 10p11.23
SPACA3 sperm acrosome associated 3 ALLP17, CT54, LYC3, LYZL3, SLLP1 17q11.2
LYZL4 lysozyme like 4 MGC26768, LYC4 3p22.1
SPACA5 sperm acrosome associated 5 dJ54B20.3, UNQ6288, LYC5, SLLP2, PNPK6288, LYZL5 Xp11.23
SPACA5B sperm acrosome associated 5B LYZL5B Xp11.23
LYZL6 lysozyme like 6 LYC1, PRO1485, TKAL754 17q12
LALBA lactalbumin alpha LYZL7 12q13.11

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