HGNC Specialist Advisors
We welcome advice from experts in particular areas of biology. The following list includes some of those who already advise the committee, and recommend appropriate new gene symbols. Please email any suggestions to hgnc@genenames.org
| Stem Symbol/Topic | Advisors |
|---|---|
| ABC | ATP-binding cassettes Dr Victor Ling BC Cancer Research Centre, BC Cancer Agency, Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada Dr Toshihisa Ishikawa Omics Science Center, RIKEN Yokohama Institute, Yokohama, Japan Dr Michael Dean Laboratory of Experimental Immunology, NCI, Frederick, MD, USA Dr Rando Allikmets Department of Ophthalmology, Columbia University, New York, NY, USA |
| ADAM | ADAM metallopeptidase domain Dr Judith M. White Department of Cell Biology, University of Virginia, Health Sciences Center, Charlottesville, VA, USA White Lab Table of the ADAMs |
| ADAMTS | ADAM metallopeptidase with thrombospondin type 1 motif Dr Suneel S. Apte Department of Biomedical Engineering, Lerner Research Institute Cleveland Clinic Foundation, Cleveland, OH, USA |
| AKR | Aldo-keto reductases Dr Trevor M Penning Department of Pharmacology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA Aldo-Keto Reductase (AKR) Superfamily Homepage |
| ALDH | Aldehyde dehydrogenases Dr Vasilis Vasiliou Department of Pharmaceutical Sciences, University of Colorado Health Sciences Center, Denver, CO, USA www.aldh.org |
| ALOX | Arachidonate lipoxygenases Dr Colin D. Funk Department of Biochemistry, Queen's University, Kingston, ON, Canada Dr Alan R. Brash Department of Pharmacology, Vanderbilt University Medical Center, Nashville, TN, USA |
| ANXA | Annexins Dr Reginald Morgan Department of Biochemistry & Molecular Biology, Faculty of Medicine, University of Oviedo, Oviedo, Spain |
| AQP | Aquaporins Dr Peter Agre Department of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA |
| ARFGAP | Arf GTPase activating protein (ArfGAP) family Dr Richard A Kahn Department of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA |
| bloodgroup | Blood group determination genes Dr Geoff Daniels International Society for Blood Transfusion Committee on Terminology for Red Cell Surface Antigens, Bristol Institute for Transfusion Sciences, Bristol, UK Committee on Terminology for Red Cell Surface Antigens |
| BPIF |
BPI fold containing family |
| CDH | Cadherin superfamily Dr Frans van Roy Paco Hulpiau Department of Molecular Biomedical Research, VIB and Ghent University, Ghent (Zwijnaarde), Belgium |
| CA | Carbonic anhydrases Dr David Hewett-Emmett Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA |
| CACN | Calcium channels Dr Philippe Lory Institut de Génomique Fonctionnelle, Département de Physiologie, CNRS UMR5203 - INSERM U661 - Universités de Montpellier I & II, Montpellier, France |
| CASP | Caspases Dr Emad Alnemri Department of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, PA, USA Dr Donald Nicholson Merck Research Laboratories, Rahway, NJ, USA Dr Guy Salvesen Program in Apoptosis and Cell Death Research, Burnham Institute for Medical Research, La Jolla, CA, USA Dr Nancy Thornberry Merck Research Laboratories, Rahway, New Jersey Dr Junying Yuan Department of Cell Biology, Harvard Medical School, Boston, MA, USA |
| CCL CCR |
Chemokines Dr Robin Thorpe IUIS Chemokine Nomenclature Subcommittee, Biotherapeutics Group, National Institute for Biological Standards and Control, UK |
| CD | CD molecules Dr Laurence Boumsell IUIS CD Nomenclature Subcommittee, INSERM U659, Faculté de Médecine, Creteil, France |
| CLDN | Claudins Dr Jeffrey Keen Molecular Medicine Unit, Clinical Science Building, St James's Hospital, University of Leeds, Leeds, UK |
| CLIC | Chloride intracellular channels Dr Mark Berryman Department of Biomedical Sciences, Ohio University College of Osteopathic Medicine, Athens, OH, USA |
| Clinical Advisor |
Clinical Advisor Dr Roberta A. Pagon Professor of Pediatrics, University of Washington, Principal Investigator, GeneTests, Editor-in-Chief, GeneReviews |
| CLK | CDC-like kinases Dr Leonard J. Rabinow Laboratoire de Signalisation, Développement et Cancer, Université Paris XI, Orsay Cedex, France |
| COLEC | Collectins Dr Kurt Drickamer Department of Biochemistry, University of Oxford, South Parks Road, Oxford, UK |
| complement | Complement system genes Dr Robert B. Sim IUIS complement subcommittee, MRC Immunochemistry Unit, Department of Biochemistry, Oxford, UK |
| CYB | Cytochrome b Dr Han Asard Department of Biology, University of Antwerp, Antwerp, Belgium |
| CYP | Cytochrome P450 Dr David R. Nelson Department of Microbiology, Immunology and Biochemistry, University of Tennessee, Memphis, TN, USA Dr Dan Nebert Department of Environmental Health, University of Cincinnati Medical Center, Cincinnati, OH, USA |
| DDX DHX |
DEAD- and DEAH-boxes Dr Mohamed Abdelhaleem Head, Division of Haematopathology, Department of Paediatric Laboratory Medicine, Hospital for Sick Children, Toronto, ON, Canada |
| DN | Dyneins (axonemal) Dr Heymut Omran Oberarzt, Universitaets-Kinderklinik, Mathildenstr. 1, 79106 Freiburg, Deutschland |
| DNAJ (Hsp40) family | DnaJ (Hsp40) family Dr Mike Cheetham Professor of Molecular Cell Biology, Division of Pathology, Institute of Ophthalmology, University College London, London, UK Dr Kenzo Ohtsuka Laboratory of Cell & Stress Biology, Department of Environmental Biology, College of Bioscience & Biotechnology, Chubu University, Kasugai, Japan |
| DYN | Dyneins (cytoplasmic) Dr Elizabeth Fisher Department of Neurodegenerative Disease, Institute of Neurology, London, UK Cytoplasmic dynein nomenclature Genetic Analysis of the Cytoplasmic Dynein Subunit Families |
| Enzyme Nomenclature |
Enzyme Nomenclature IUBMB Enzyme Nomenclature EXPASY Enzyme nomenclature database |
| FANC | Fanconi anemia,complementation groups Prof. Hans Joenje Department of Clinical Genetics, VU University Medical Center, Amsterdam |
| FOX | Forkhead box genes Dr Daniel E. Martínez Department of Biology, Pomona College, Claremont, CA, USA |
| GJ | Gap junction proteins (connexins) Dr Thomas W. White Department of Physiology and Biophysics, Stony Brook University, NY, USA |
| GPCR |
G-protein coupled receptors |
| Histones | Histones Dr David Landsman Chief, Computational Biology Branch, NCBI, NLM, NIH, Bethesda, Maryland, USA |
| HLA | Histocompatibility complex Dr Steven G. E. Marsh Anthony Nolan Research Institute, Royal Free Hospital, London, UK IMGT/HLA Database |
| High mobility group | High mobility group Dr Michael Bustin Chief, Protein Section, Laboratory of Metabolism, CCR, NCI, NIH, Bethesda, MD, USA Dr David Landsman Chief, Computational Biology Branch, NCBI, NLM, NIH, Bethesda, MD, USA |
| Homeobox gene family | Homeobox Dr Peter W H Holland Linacre Professor of Zoology, Department of Zoology, University of Oxford, Oxford, UK |
| Immunodeficiences | Immunodeficiencies Dr Jennifer M. Puck Genetics and Molecular Biology Branch, National Human Genome Research Institute, Bethesda, MD, USA Dr Hans D. Ochs Department of Pediatrics, Division of Immunology, Infectious Diseases and Rheumatology, University of Washington School of Medicine, Seattle, WA , USA Dr C. I. Edvard Smith Clinical Research Center, Karolinska Institutet at Novum, Huddinge, Sweden |
| Immunological Nomenclature |
Immunological Nomenclature Laurence Boumsell IUIS Nomenclature Committee |
| IFN | Interferons Dr Erik Lundgren ISICR Nomenclature Committee, Department of Molecular Biology, Umeå University, Umeå, Sweden |
| IG | Immunoglobulins Dr Marie-Paule Lefranc Laboratoire d'ImmunoGénétique Moléculaire, IGH, UPR CNRS 1142, Montpellier, France IMGT The International ImMunoGeneTics information system® |
| IL | Interleukins and interleukin receptors Dr John Schrader IUIS Interleukin Nomenclature Subcommittee. Director of The Biomedical Research Centre,University of British Columbia, Vancouver, BC, Canada |
| IPO XPO |
Importins and Exportins Dr Dirk Görlich Department of Cellular Logistics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany |
| KCN | Potassium channels Dr Florian Lesage Institut de Pharmacologie Moléculaire et Cellulaire, CNRS, and Université de Nice Sophia Antipolis, Valbonne, France |
| KIF | Kinesins Dr Nobutaka Hirokawa Department of Cell Biology and Anatomy, Graduate School of Medicine, University of Tokyo, Tokyo, Japan |
| KIR | Killer cell immunoglobulin-like receptors Dr Steven G. E. Marsh Anthony Nolan Research Institute, Royal Free Hospital, London, UK Dr Peter Parham Department of Microbiology & Immunology, Stanford University School of Medicine, Stanford, CA, USA Dr John Trowsdale Department of Pathology, University of Cambridge, Cambridge, UK Dr Mary Carrington Laboratory of Experimental Immunology, NCI, Frederick, MD, USA IPD - KIR Database |
| KLF | Kruppel-like factors Dr Merlin Crossley Department of Biochemistry, University of Sydney, NSW, Australia |
| KLK | Kallikreins Dr Eleftherios P. Diamandis Department of Pathology and Laboratory Medicine, Mount Sinai Hospital and Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada Dr Åke Lundwall Lund University, Department of Laboratory Medicine, Division of Clinical Chemistry, University Hospital MAS, S-205 02 Malmö, Sweden |
| KRT | Keratins Dr Michael A. Rogers German Cancer Research Center, Research Program 2, Im Neuenheimerfeld 280, 69120 Heidelberg, Germany |
| Methyltransferases | Methyltransferases Dr Janusz Bujnicki Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology, Warsaw, Poland |
| MIR | microRNAs Dr Sam Griffiths-Jones Faculty of Life Sciences, University of Manchester, Michael Smith Building, Oxford Road, Manchester, UK miRBase |
| MRPL MRPS |
Mitochondrial ribosomal proteins Dr Naoya Kenmochi Frontier Science Research Center, University of Miyazaki, Kiyotake, Miyazaki, Japan |
| MRX | X-linked mental retardation Dr Ben C.J. Hamel Department of Human Genetics, University Hospital Nijmegen, The Netherlands |
| MUC | Mucins Dr Dallas Swallow Research Department of Genetics, Evolution and Environment, University College London, London, UK Mucin Group Homepage |
| Myosin superfamily | Myosin superfamily Dr Richard Cheney Department of Cell and Molecular Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA Dr Jonathan S. Berg Curriculum in Neurobiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA |
| ncRNAs (non-protein-coding RNAs) |
Long Non-coding RNA (lncRNA) Micro RNA (miRNA) Piwi-interacting RNA (piRNA) Ribosomal RNA (rRNA) clusters Small nucleolar RNAs (snoRNA) U7 RNA and vault RNA (vtRNA) |
| Nuclear receptors |
Nuclear receptors Prof Vincent Laudet Institut de Génomique Fonctionnelle de Lyon (IGFL), Lyon, France |
| NUDT | Nudix motif-containing Dr Alexander G. McLennan School of Biological Sciences, University of Liverpool, , Liverpool, UK |
| OR | Olfactory receptors Dr Doron Lancet Dr Tsviya Olender Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel |
| OSBP | Oxysterol binding proteins Dr Cynthia J. Jaworski Laboratory of Retinal Cell and Molecular Biology, NIH, Bethesda, MD 20892, USA |
| Peptidases | Peptidases Dr Alan J Barrett Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK Handbook of Proteolytic Enzymes MEROPS - the Peptidase Database IUBMB EC List for Peptidases |
| P2R | Purinergic receptors Dr Brian King Autonomic Neuroscience Institute, Royal Free Hospital School of Medicine (RFHSM), Hampstead, London, UK |
| PPP1R | Protein phosphatase 1, regulatory family Dr Mathieu Bollen Division of Biochemistry, Faculty of Medicine, Katholieke Universiteit, Leuven, Belgium |
| Protein kinases |
Protein kinases Dr Gerard Manning Dr Tony Hunter The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA, USA |
| PRMT | Protein arginine methyltransferases Dr Steven Clarke Department of Chemistry & Biochemistry, UCLA, Los Angeles, CA, USA Dr Mark T. Bedford University of Texas, M.D. Anderson Cancer Center, Department of Carcinogenesis, Smithville, Texas, USA |
| PSM | Proteasome (prosome, macropain) Dr Keiji Tanaka Department of Molecular Oncology, The Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan |
| PTP | Protein tyrosine phosphatases (including dual specificity phosphatases) Dr Jannik Andersen Merck Sharp & Dohme, Boston, MA, USA |
| RAB | RAB, member RAS oncogene family Dr Miguel C. Seabra Cell and Molecular Biology, Division of Biomedical Sciences, Faculty of Medicine, Imperial College, London, UK |
| RGS | Regulator of G-protein signalling Dr David P. Siderovski Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA |
| RPL RPS | Ribosomal proteins Dr Naoya Kenmochi Frontier Science Research Center, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki, Japan |
| SCGB | Secretoglobins Dr Joerg Klug Justus-Liebig-Universitaet Giessen, Institut fuer Anatomie und Zellbiologie, D-35385 Giessen, Germany |
| SC | Sodium channels Dr William A Catterall Department of Pharmacology, University of Washington School of Medicine, Seattle, WA 98195-7280, USA |
| SEMA | Semaphorins Dr Alex L. Kolodkin Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA |
| SERPIN | Serine (or cysteine) peptidase inhibitors Dr Gary A. Silverman Dept of Pediatrics, Harvard Medical School, and Division of Newborn Medicine, Children's Hospital, Enders 9, Boston, MA, USA |
| SIGLEC | Sialic acid binding Ig-like lectins Dr Ajit Varki Department of Cellular and Molecular Medicine and Director, Glycobiology Research and Training Center, University of California, San Diego, La Jolla, CA, USA |
| SLC | Solute carrier superfamily Dr Matthias A. Hediger Institute of Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland |
| SOX | SRY (sex determining region Y)-box Dr Peter Koopman Institute for Molecular Bioscience, The University of Queensland, Brisbane, Australia Koopman Laboratory |
| TBX | T-box family Dr Jeremy Gibson-Brown Department of Biology, Washington University, St Louis, MO, USA |
| TNFSF TNFRSF |
Tumor necrosis factor and receptor superfamilies Dr Carl F. Ware Laboratory of Molecular Immunology, Infectious and Inflammatory Disease Center, Sanford-Burnham Medical Research Institute, La Jolla, CA, USA |
| TR | T cell receptors Dr Marie-Paule Lefranc Laboratoire d'ImmunoGénétique Moléculaire LIGM, UPR CNRS 1142, IGH, Montpellier, France IMGT The International ImMunoGeneTics information system® |
| TRIM | Tripartite motif-containing family Dr Alexandre Reymond Center for Integrative Genomics, Genopode building, University of Lausanne, Lausanne, Switzerland |
| TRP | Transient receptor potential cation channels Dr Craig Montell Department of Biological Chemistry, The Johns Hopkins School of Medicine, Baltimore, MD, USA Dr Lutz Birnbaumer Division of Intramural Research, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA Dr Veit Flockerzi Institut für Experimentelle und Klinische Pharmakologie und Toxikologie, Universität des Saarlandes, Homburg/Saar, Germany |
| UGT | UDP glycosyltransferases Dr Peter I Mackenzie Department of Clinical Pharmacology, Flinders University School of Medicine, Flinders Medical Centre, Bedford Park, SA, Australia UDP Glucuronosyltransferase Homepage |
| USP | Ubiquitins Dr Rohan Baker Ubiquitin Lab, Molecular Genetics Group, John Curtin School of Medical Research, Australian National University, Canberra, ACT, Australia |
| WNT | WNT wingless-type Dr Roel Nusse Howard Hughes Medical Institute, Dept. of Developmental Biology, Stanford University School of Medicine, Beckman Center, Stanford, CA, USA The WNT Homepage |
| ZDHHC | Zinc fingers, DHHC type Dr Susan Gentleman Laboratory of Retinal Cell and Molecular Biology, National Eye Institute, NIH, Bethesda, MD, USA |
| ZNF | Zinc fingers, C2H2 type Dr Lisa Stubbs Institute for Genomic Biology, University of Illinois at Urbana Champaign, Urbana, IL |
